Regulatory epigenetic changes to genomic regions in the brain are essential for human cognition and mental health.
A new method, dubbed DREADDs, relies on gene therapy techniques to alter genes in target cells to change the cell’s behavior. The method reduced anxious behaviors in monkey models of schizophrenia when combined with clozapine. Researchers say the metho…
Researchers have uncovered the molecular structure of three major complexes of glutamate receptors in the hippocampus. The findings shed new light on the mechanisms behind memory and learning in the brain.
A link has been identified between psychosis and a genetic change that alters the immune system in the brain. Researchers found people with psychosis associated with bipolar disorder had decreased expression of GRK3. This led to an increased amount of …
Combining αGITR antibodies with ICBs resulted in stronger survival benefits in mouse models of human glioblastoma brain cancer.
Parapinopsin, a protein found in lamprey, is being used by researchers to manipulate brain circuitry. The protein is able to switch off specific brain circuits.
If you feel anxious while at the wheel, you are more likely to feel exhaustion when you arrive at your destination, a new study reports.
BARseq2 is a new technique that allows researchers to trace thousands of brain circuits simultaneously.
Study reveals the molecular clues as to why some neurons are susceptible to death in Alzheimer’s disease while others aren’t.
When necrotic cells expose phosphatidylserine on their outer surfaces, and when phagocytes detect it, the phagocytes ingest and destroy the dying cells.
Researchers identify five genetic loci linked to the progression of Parkinson’s disease.
The cerebellum underwent evolutionary changes that may have contributed to the development of language, culture, and tool use in humans, a new study reveals.
Findings suggest developing HDAC6 inhibitors could be a novel new therapeutic avenue for the treatment of migraines.
Mouse study reveals females with the EPHB2 genetic mutation are at greater risk of autism.
Novel gene therapy treatment prevents learning impairments and memory loss in mouse models of Alzheimer’s disease.
Study reveals people who live to be 105 or older have unique genetic signatures that are linked to more efficient DNA repair.
New genetic findings related to circadian rhythm could have implications for humans, animals, and even plant life.
People born into families with members who live longer lives show better cognitive performance and a slower decline in cognitive processing speed as they age.
A 3D mini brain, created from human skin cells, will be used to study myelin.
Using single nucleus RNA sequencing, researchers have mapped 21 subtypes of motor neurons in the spinal cords of mice.